Most recreational users of Psilocybe cubensis (when grown in vitro) require a dosage of 1 to 2 gm of dried mushrooms to produce an altered state of consciousness; a clinical dosage for Psilocybe cubensis, on the other hand, had previously been reported as ranging from 3 to 5 gm of dried material. This dosage would be comparable to the amount of fungal material consumed for religious purposes in a Mazatec Indian healing and curing ceremony. In 1982, one research team "found that the level of psilocybin and psilocin varies over a factor of 4 among various in vitro cultures of Psilocybe cubensis, while specimens from outdoors varied tenfold." A fresh dosage of Psilocybe cubensis in Australia would be approximately from 1 to 2 large mushrooms weighing up to as much as one fresh ounce, or as many as from 25 to 50 small mushrooms equaling the same weight amount. Ethnopharmacologist Jonathan Ott (1976, 1993) noted that he has observed "the ingestion of from 0.5 gm to 5.9 gm dried weight (10 gm to 40 gm fresh)", of various species of Psilocybe. Dosage for Psilocybe subcubensis would be the same as for Psilocybe cubensis. Both of these latter two species are macroscopically alike. The usual dosage for Copelandia cyanescens required to induce psychedelic visual effects ranges from 1 to 3 large specimens (cap diameter c. 5 mm), or as many as 5 to l0 medium-sized mushrooms (cap diameter c. 2.5 mm); however, personal tolerance to this species may occur with continued use, and some who consume large amounts of this mushroom have reportedly ingested as many as 50 to 200 fresh specimens of various sizes. Ls Seeds Outdoor 1033 Pm19
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